Human Formiminotransferase Cyclodeaminase (LC-1)

$473.79

SIZE

0.1 mg

INTRODUCTION

LC1 is an enzyme which catalyzes the conversion of formiminoglutamate and tetrahydrofolate into formiminotetrahydrofolate and glutamate. As a bio-functional enzyme of tetrahydrofolate synthesis, it is the target antigen of anti-LC1 (liver cytosol antigen type 1) autoantibodies. Presence of LC1 autoantibodies is a marker for type 2 autoimmune hepatitis.

DESCRIPTION

Expressed in insect Sf9 cells with a total 565 AA.

Mw: 61.9KDa (calculated).

N-terminal 6xHis-tag and TEV cleavage site, extra 25 AA (highlighted).

Recombinant antigen for research use or manufacturing only.

SIZE

0.1 mg

INTRODUCTION

LC1 is an enzyme which catalyzes the conversion of formiminoglutamate and tetrahydrofolate into formiminotetrahydrofolate and glutamate. As a bio-functional enzyme of tetrahydrofolate synthesis, it is the target antigen of anti-LC1 (liver cytosol antigen type 1) autoantibodies. Presence of LC1 autoantibodies is a marker for type 2 autoimmune hepatitis.

DESCRIPTION

Expressed in insect Sf9 cells with a total 565 AA.

Mw: 61.9KDa (calculated).

N-terminal 6xHis-tag and TEV cleavage site, extra 25 AA (highlighted).

Recombinant antigen for research use or manufacturing only.